I’m currently on PopOS 22 and I’m in the mood to try something different. I mostly game but I do need my system to have support for the everyday tasks I sometimes need to do, so I fell bazzite is a no go.
I see a lot of people recommending Cachy, will it be a smooth experience for someone used to linux? Is Endeavour a better choice? Will I have issued with my PS3 eye camera and x52 stick?

Gaming on the GNU/Linux operating system.
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I was under the impression that their aggressive pruning of things usually used for workstation tasks would hamper a sane use of it. From what I’ve gathered they even removed the usual python bins that come with most linux distros these days, as an example.
Universal Blue does things differently from traditional distros and their philosophy is very cloud/container based.
They specifically have the Bluefin variant for workstation and software development use:
https://projectbluefin.io/
I don’t know what any of that means but I haven’t encountered anything that prevents me from using it on my workstation. Sounds like you may have a more advanced usecase.