uBlock and the right Firefox settings is good enough in my opinion, you can go really crazy with just those two things but you’ll also break a lot of sites, I found a middle ground that I like.

This is just my personal list

• Ublock origin in advanced mode to block js like matrix did (or in basic mode on mobile/if you don’t want to waste time fixing broke websites)
• Decentraleyes to avoid loading libraries
• Cookies autodelete to you guess it
• Consent O Matic to auto consent gdpr banners
• Link cleaner to clean copied urls from tracking queries
• Redirector to redirect famous websites to their alternative front-ends (YouTube to piped etc)

I go pretty hard core while making sure it “just works”. People will mention LibreWolf, but the fingerprint resistance causes too much breakage for me. I install uBlock Origin no matter what, enable every single filter except the language lists. I install Dark Reader and set it to a timed schedule which is comfy for me.

Then I install NoScript then enable “Temporary set top level sites to trusted” and enable media under the trusted tab. This fixed majority of the breakage, but you sometimes need to tweak it. You can just not use NoScript if it’s too much of a hassle, uBlock Origin does basically everything you need anyways.

Also of course if you’re using stock Firefox, make sure to turn off analytics and telemetry in the settings, go to about:config and set pocket.enabled (or something like that, idr) to false. Then I set my default search to duckduckgo.